When the Captain of the Enterprise states that the mission is "to explore strange new worlds; to seek out new life and new civilizations; to boldly go where no one has gone before"—what is the real-world translation of such a statement? Science fiction powerhouse Roddenberry Entertainment has brought together some of the preeminent scientists from NASA's Jet Propulsion Laboratory and experts in astronomy to break down what making contact with alien civilizations might entail and how we are working to make this science fiction fantasy into a concrete reality. Panelists include Rekha Sharma (Ellen Landry, Star Trek: Discovery; Tory Foster, Battlestar Galactica), James Tuttle Keane (co-investigator for the NASA Discovery Io Volcano Observer mission proposal; NASA New Frontiers New Horizons mission science team member), and Jordan Ticktin (aerospace systems engineer), with moderator Tamara Krinsky (Marvel Red Carpet host; Tomorrow’s World Today).